In vitro cytotoxic activity of Tarantula cubensis alcoholic extract on different human cell lines

نویسندگان

چکیده

Spider venoms are known to have great potential for their antimicrobial, antifungal, and antitumor activities due rich peptide content. Tarantula cubensis alcoholic extract Theranekron® is a homeopathic remedy it frequently used in veterinary treatments. Specifically, the anti-inflammatory, wound healing effects of provide wide range use animal More importantly, can reduce growth rate canine mammary tumors. This effect shows that be candidate cancer treatment. In this study, cytotoxic was evaluated four different human cell lines one non-cancerous line. It aimed foundation further studies by conducting an vitro screening Theranekron®. Results showed has high on breast lines. On other hand, cytotoxicity found relatively lower small lung cancer, glioblastoma prostate as compared cells. These results indicated T. might utilized anticancer bio-therapeutic should examined its potential.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cytotoxic Effects of Artemisia annua Methanol Extract on Cancer Cell Lines in Vitro

Background & Aims: In most cases, drugs used for the treatment of cancer are not effective or have unpleasant side-effects. This has forced scientists to find more effective drugs with less toxicity. Artemisia is an important medicinal plant in the world and anti-tumoral activity of some Artemisia species has been reported. This study was designed for evaluation of anti-tumoral effect of methan...

متن کامل

In Vitro Cytotoxic Effects of Cuscuta chinensis Whole Extract on Human Acute Lymphoblastic Leukemia Cell Line

Background: One of the major paths for drug development is the study of bioactivities of natural products. Therefore, the aim of this study was to compare the cytotoxic effects of aqueous extract of whole Cuscuta chinensis Lam., which is a traditional medicinal herb commonly used in Iran and other oriental countries, on the human caucasian acute lymphoblastic leukemia (CCRF-CEM) and another hum...

متن کامل

Comparison of cytotoxic activity of some Iranian Stachys spp. extracts on different cancer cell lines

The genus Stachys belongs to Lamiaceae family with about 300 species and worldwide distribution. In the present study, the cytotoxic activity of four fractions of different Satchys species (S. byzatina C. Koch., S. inflata Benth., S. setifera Ten. and S. persica Gmel.), has been investigated against HT-29 (colon carcinoma), Caco-2 (colorecta...

متن کامل

CYTOTOXIC ACTIVITY OF THYMUS VULGARIS, ACHILLEA MILLEFOLIUM AND THUJA ORIENTALIS ON DIFFERENT GROWING CELL LINES

The cytotoxic activity of ethanolic extracts of Thymus vulgaris, Thuja orientalis and Achillea millefolium was investigated on various growing tumor cell lines. MTT colorimetric assay was used for measuring the inhibition of cell proliferation. All of the three extracts showed a relatively dose-dependent inhibition of proliferation of human breast cancer (SK-Br-3, MDA-MB-435) and leukemia ...

متن کامل

Comparison of Cytotoxic Activity of Bile on HepG2 and CCRF-CEM Cell Lines: An in Vitro Study

The aim of this study was to examine the effect of crude bile on the human HepG2 and CCRF-CEM cell lines. Cells were exposed to different dilutions of bile. Antiproliferative effects were determined by the cytotoxic MTT assay. Cells undergoing apoptosis were identified by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. Bile administration resulted in dose-dependent c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Cumhuriyet Science Journal

سال: 2021

ISSN: ['2587-2680', '2587-246X']

DOI: https://doi.org/10.17776/csj.859132